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These hormones include estrogens, progesterone, DHEA, testosterone, and pregnenolone

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3 Here we describe an integrated chemical, pharmacological and structural approach to elucidate mechanisms of signal transduction by the glucagon-like peptide-1 receptor (GLP-1R), based on comparisons involving two natural agonists, GLP-1 and exendin-4, and rationally designed analogues of these peptides