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Implications for employers: - Direct purchase from a pharmaceutical company of GLP-1 medications effective in obesity treatment at this point remains cost-prohibitive for most plan members with obesity who do not have coverage in their employer-sponsored plans

198 B22, a novel indolinone derivative, inhibits CTSC activity and has been reported to reduce both inflammation and cytokine levels, 199 highlighting CTSC as a potential therapeutic target for limiting disease progression in pancreatitis

Several factors contribute to this efficacy difference