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Descrito pela primeira vez em 1993 por Sikiri et al., apresenta notvel estabilidade qumica, mantendo a atividade biolgica mesmo no ambiente gastrointestinal cido uma propriedade que o distingue da maioria dos peptdeos teraputicos

Pentadeca Arginate is almost a mirror image of BPC-157 features the same 15 amino acid sequence as BPC-157, but includes an added arginate salt to enhance its stability

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However, if influx via one or both sources is reduced or postsynaptic calcium is partially buffered, only the threshold for LTD induction is reached