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Furthermore, the cardiovascular disease prevention criteria resulted in the qualification of around 8.9 million adults aged 45 and older who met the eligibility criteria due to a high BMI and a history of major cardiovascular events, such as myocardial infarction or stroke

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However, 55.7% of these patients either remained around the weight they were at when stopping the medication or continued to lose additional weight

Our results suggest that semaglutide use could extend beyond managing diabetes, potentially offering unexpected benefits in the treatment and prevention of cognitive decline and substance misuse, said Dr Riccardo De Giorgi, Clinical Lecturer at the University of Oxford and lead author of the study