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To investigate the role of USCs in bladder remodelling, we isolated bladder USCs from convalescent mice (4 weeks after the initiation of antibiotics), from both those with self-resolved infection (resolved) and those that developed chronic infection (sensitized), as well as from age-matched nave mice as controls and established USC lines ( n = 4 per infection history) (Fig

Discontinuation may result in weight regain, and some patients experience mild gastrointestinal side effects during the initial phase of treatment

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The PHQ-9 takes less than 3 min to complete, and has demonstrated excellent diagnostic accuracy in large individual-participant-data meta-analyses [127]