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Or more specifically, non-arteritic anterior ischemic optic neuropathy or NAION

The outer ring depicts major hallmarks of aging that are positively modulated by GLP-1R signaling, including genomic instability, telomere attrition, epigenetic alterations, cellular senescence, stem cell exhaustion, chronic low-grade inflammation (inflammaging), insulin resistance, mitochondrial dysfunction, altered intercellular communication, dysregulated nutrient sensing, and microbiome dysbiosis