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How reconstitution creates concentration A vial containing 5 mg of lyophilized semaglutide powder becomes a specific concentration based on how much bacteriostatic water you add: Add 1 mL of water: 5 mg/mL concentration Add 2 mL of water: 2.5 mg/mL concentration Add 5 mL of water: 1 mg/mL concentration More water means lower concentration, which means more units per dose but easier measurement

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Most people get enough vitamin B12 in their diet, but a deficiency may occur in certain health conditions (such as poor nutrition, stomach/intestinal problems, infection, cancer)

Both medications were given as once-weekly injections for a total of 72 weeks