In this paper, we review the literature on ferroptosis and its relationship with cancer from different perspectives, including proto-oncogene and tumor suppressor gene, epigenetics, cancer stem cells (CSCs), and the tumor microenvironment (TME)
Officioso A, Alzoubi K, Manna C, Lang F
We now report that miR-4488 quenches inflammation-associated gene expression in such metabolically perturbed cells
Specifically, KPV is a fragment of alpha-melanocyte-stimulating hormone (-MSH), a larger peptide with anti-inflammatory, antimicrobial, and fever-reducing properties.1 Even more specifically, the fragment in question is the C-terminal region of -MSH, which is particularly good at neutralizing pathogens.2 While many therapeutic peptides are taken exclusively by needle, KPV stands apart in that it can also be administered as an oral capsule or chewable tablet