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Intracellular production of OH from H 2 O 2 is driven by the Fenton reaction, shown in Reaction 3 ( As the most reactive known ROS, OH reacts with nearly all intracellular building blocks and macromolecules (amino acids, nucleic acids, phospholipids, sugars, proteins, RNA, DNA, lipids, polysaccharides)

In a double-blind, randomized, controlled clinical trial, LAC was not inferior to amisulpride in relieving symptoms of dysthymic patients, showing an excellent profile of safety and tolerability [61]

Purity: 98% by HPLC (verified by Certificate of Analysis)

Its activity is studied through copper transport and signaling interactions rather than one receptor