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Livers were excised quickly, trimmed, rinsed in ice-cooled 0.9% (w/v) saline to remove blood, blotted dry and weighed at temperature of 0 to 4C

En un subestudio del ensayo de fase 3 SURPASS-3, en pacientes con DM2 y esteatosis heptica, tirzepatida, tras 52 semanas de tratamiento en dosis de 10mg y 15mg, redujo significativamente el contenido de grasa heptica con una diferencia estimada de 4,71% frente a insulina degludec24

Typical timelines for obesity drugs from Phase 1 to FDA approval run five to seven years