Western diets high in sugar, fat, and n-6 PUFA disrupt the gut barrier by increasing pro-inflammatory mediators, whereas Mediterranean diets rich in dietary fiber, plant polyphenols, and n-3 PUFA enhance microbiota diversity and promote the production of anti-inflammatory metabolites, such as SCFAs, thereby alleviating intestinal inflammation [247,248,249]
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Ongoing Support To maintain optimal energy levels and overall health, regular B12 injections may be recommended
Modulation of Oxidative Stress and Central Mechanisms in Neuropathic Pain: Molecular Pathways, Mitochondrial Protection, and Clinical Implications Oxidative stress, which results from an imbalance between ROS and the bodys antioxidant defenses, is a key mechanism in the pathogenesis of neuropathic pain [84]