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HGF/SF is present in normal adult skeletal muscle and is capable of activating satellite cells

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doi:10.3390/ijms19092530 Liang ZT, Li J, Rong R, et al

The mechanisms underlying these effects include the inhibition of protein tyrosine phosphatase 1B (PTP1B), which is physiologically responsible for insulin receptor inhibition through dephosphorylation and attenuates insulin signal transduction (123, 124)