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15 The biologic consequences of the activation and degranulation of mast cells in the rheumatoid synovial tissue are complex and despite their ability to mediate inflammation was neglected for years, the mast cell and its products are now recognized as novel targets for therapy of rheumatoid arthritis

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Reconstitution Math Vial contents: 5 mg cagrilintide + 5 mg Semaglutide = 10 mg total blend Add: 3.0 mL bacteriostatic water Concentration: 10 mg 3.0 mL = 3.33 mg/mL total (1.67 mg/mL each peptide) Per unit (U100 syringe): 3333 mcg/mL 0.01 mL = 33.3 mcg total per unit (16.7 mcg each peptide) Reconstitution Steps Draw 3.0 mL bacteriostatic water with a sterile syringe