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In contrast, GSH depletion drives M1 polarization, resulting in heightened secretion of pro-inflammatory cytokines, including TNF-, IL-6, and IL-1 ( Overall, GSH helps limit unwanted immune attacks in the brain

One possible idea is that the phenotype of glp-1(oz112) or glp-1(ar202) mutants may be stronger than that of glp-1(bn18) mutants

[DOI] [PMC free article] [PubMed] [Google Scholar] 5.Healthy diet and lifestyle improve the gut microbiota and help combat fungal infection

Thus, significant efforts are presently directed at designing drugs capable of slowing the progression of disease symptoms, with the ultimate goal of halting and reversing the underlying causes of AD