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As the number of post-mortem studies are limited, it is unclear whether these findings are true representations of regional expression variations between the hippocampus and cerebellum

Canadian researchers at McMaster University have published extensively on this topic, demonstrating that body composition quality predicts long-term weight maintenance success better than total pounds lost

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But there are several obstacles to the development of this senolytic approach such as the long-term effect of CAR-T cells therapy with possible aspecific toxicity in different organs 56 , the cost and the difficulty during process development 57 or the selection of non-exhausted T cells to generate efficient therapy 58,59