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In short: the risk remains theoretical

We observed a change of 40% in plasma ascorbate from the second month and a leukocyte ascorbate change of 28% from the third month to the end of the study, respectively

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Very low body fat People with very low body fat percentages (typically below 10-12% for men or 18-20% for women) may not have sufficient subcutaneous tissue on the thigh for reliable subcutaneous injection