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The maternal microbiome plays a critical role in modulating the infant gut microbiome, immune system and its subsequent role in the gut-brain axis, and fermented foods inherently act as probiotics

It is understood that blood components such as red blood cells will be removed and reintroduced to the circulatory system

Although, there are various therapeutic methods for OA, such as surgery, drug and adjuvant therapy, it is difficult to completely stop the development of OA, which results in continuous pain and even long-term disability [6]

It is also very important to collect pre-treatment specimen or any specimen as early as possible for laboratory investigation as treatment might alleviate or alter the biochemical derangement and thus the laboratory results