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Critically, subcutaneous fat was not meaningfully reduced in the pivotal studies

[DOI] [PMC free article] [PubMed] [Google Scholar] 102.Remington JP

Theres a problem, though

In humans, a recent systematic analysis of reported gastrointestinal side effects during treatment with GLP1 receptor agonists, including 32 clinical trials and 10,367 patients, reports that the level of nausea and vomiting depends on several factors: (i) the higher the dose, the higher the frequency of nausea, (ii) other medication and (iii) longacting GLP1 receptor agonists compared with more shortacting GLP1 receptor agonists, were associated with less nausea (Bettge et al., 2017)