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The clinical manifestation of the autoimmune phenotype towards HT or GD largely depends on the balance of the immune response induced by T-helper cells (Th1 or Th2), antigen-presenting cells (APCs) and the cytokine profile that dominates at that moment in the thyroid parenchyma (26)

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Consistent with these findings, data from the Clinical Proteomic Tumor Analysis Consortium (CPTAC) dataset confirmed that ETV6 protein levels were significantly higher in EC tumors compared to normal controls (Fig