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Ca 2+ -dependent endoplasmic reticulum stress correlates with astrogliosis in oligomeric amyloid -treated astrocytes and in a model of Alzheimers disease

Continued research into novel GLP-1 agonists and combination therapies will further refine their role

In colonic tissue models, gabapentin was associated with: Reduced mast cell density or activation markers Decreased release of inflammatory mediators Improvement in visceral pain signaling These findings suggest gabapentin may exert indirect mast cellregulating effects within colonic tissue in experimental models