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Burrows DJ, McGown A, Jain SA, De Felice M, Ramesh TM, Sharrack B et al

GLP-1s can lead to excessive muscle loss and amplify an already existing protein deficiency crisis in Indian diets across States and communities

GLP-1RAs can downregulate the expression of the myostatin gene in C2C12 myotubes, reversing the upregulation of atrophy factors and downregulation of myogenic factors (MyoD/G) (136)