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Ghaderi, S
Because SAM is also required for many other methylation reactions, including gene-expression regulation, high NNMT activity draws heavily on SAM and is associated in studies with reduced NAD, a coenzyme central to cellular energy production
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also activates a second gut hormone receptor, GIP (glucose-dependent insulinotropic polypeptide) Plot twist: GLP-1 receptors are scattered throughout the body - including on immune cells and in the ovaries Here's where it gets interesting
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