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It has been shown to increase fat oxidation and energy expenditure by activating REV-ERB/ nuclear receptors, which are central to lipid metabolism and biological clock regulation

Vitamin B12 supplements are recommended to population groups at higher risk for developing vitamin B12 deficiency: everyone (no matter what their diet) over 50 years old, people with diseases of the gastrointestinal system such as Chrohns and IBS, women on oral contraceptives and people who regularly use nitrous oxide or are alcoholics

Acknowledgments The authors thank the Faculty of Medicine at Al-Quds University for academic support

Visible results may appear within weeks of commencing treatment