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A report from the Framingham Offspring Study of 2,999 adults found the following average daily B12 intakes, including fortified foods and supplements (Tucker, 2000): Age 26-49: 8.9 g Age 50-64: 8.7 g Age 65-83: 8.5 g A 2015-2016 National Health and Nutrition Examination Survey of over 4,500 adults 60 years and older found the following average daily B12 intakes (USDA NHANES, 2019): Male non-supplement users (68% of men): 4.5 g Male supplement users: 5.3 g from food plus 326 g from supplements Female non-supplement users (63% of women): 3.6 g Female supplement users: 3.8 g from food plus 520 g from supplements European Food Safety Authoritys Recommendations In 2015, the EFSA released recommendations for B12 intake across Europe

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A single-center, double-blinded, randomized controlled study to evaluate the relative efficacy of sublingual and oral vitamin B-complex administration

IGF-1 LR3 Reconstitution Reference (0.1 mg / 100 mcg vial) BAC water added 0.5 mL Concentration 200 mcg/mL 20 mcg dose 0.10 mL (10 units) 40 mcg dose 0.20 mL (20 units) 50 mcg dose 0.25 mL (25 units) BAC water added 1 mL Concentration 100 mcg/mL 20 mcg dose 0.20 mL (20 units) 40 mcg dose 0.40 mL (40 units) 50 mcg dose 0.50 mL (50 units) Smaller vials are typically used for short cycles or first-cycle assessment