In the early stage of heat stroke, abdominal B-ultrasound and liver computed tomography (CT) usually show no obvious abnormalities
Cohort entry was defined as the date of the first-ever prescription for one of the drugs of interest (GLP-1RAs, SGLT2 inhibitors, metformin or other second- or third-line glucose-lowering drugs) during the study period, and their respective first exposure was defined as the index event
Briefly, 1 mL of assay mixture contains optimized concentrations of the following chemicals: 0,5 M K 2 HPO 4 (pH 7.0), 2,5 mM EDTA, 0,18 U/mL GR, 100 mM glutathione and 10 mM reduced NADPH and tissue extract (0,5 mL) was added in the spectrophotometer cuvette along with 0,1 mL of 60 mM cumene hydroperoxide, a suitable substrate for GP
doi: 10.1080/17451000.2022.2101122 123