Activated microglia serve a dual role during ischemia, releasing pro-inflammatory cytokines (such as TNF- and IL-1) that can aggravate ischemic injury, whilst promoting the release of anti-inflammatory cytokines (such as IL-10) to reduce ischemic injury [2]
May 5, 2020 David Sinclairs Supplement Regimen: NMN, Resveratrol, Metformin, Vitamin D, Vitamin K and the Science of Longevity David Sinclairs Supplement Regimen: NMN + Resveratrol : 1 g of NMN and 0.5 g of resveratrol every morning mixed in with some yogurt David never shares brand names, but we know and trust 2 in particular: Elysium Basis : NR/pterostilbene Combo, NR is a smaller variant of NMN that has been shown to be better at entering cells We at Podcast notes have tried Basis ourselves and have heavily vetted their quality and supply chain Thorne ResveraCel : 300mg NMN + 150mg Resveratrol + 250mg Quecitin We use Throne products as frequently as we can given their quality and on Rhonda Patricks recommendation Vitamin D + K2 Metformin : 1 g at Night High Dose Statin (he has genetically driven high cholesterol) David Sinclairs Diet Intermittent Fasting : Skip breakfast/lunch on most days Eat as many vegetables/leafy greens as possible Resveratrol is just one of a bunch of polyphenols that plans make when theyre stressed 1 cup of coffee in the morning Avoid Sugar and Carbs Limit protein intake, and specifically red meat Why
Gentle yet effective formula: Contains panthenol, glycerin and allantoin to soothe, hydrate and support the skin barrier, delivering results without irritation
It does this by slowing down how quickly food leaves the stomach, reducing hunger signals in the brain, and making people feel full sooner
