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Abstract Diabetes mellitus (DM), a metabolic disorder syndrome characterized by persistent hyperglycemia, has a complex pathogenesis

A previous study using labeled cholesterol has demonstrated that the circulating cholesterol level was elevated during the zero-calorie fasting period due to the release of the lipid droplets from adipose tissues [40]

This reduces the complications from diabetes but also controls hunger and helps with weight loss in combination with routine exercise

GLP-1 receptor agonists in heart failure GLP-1 receptor agonists have demonstrated favorable cardiovascular effects in patients with T2DM and obesity as meta-analyses suggest a reduction in hospitalization for incident or new-onset HF of approximately 18%, alongside reductions in major adverse cardiovascular events [6, 14, 15]