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[29] A 1999 clinical dose ranging study in "eight male volunteers with 'tannable' skin types III-IV" given [Nle 4 , D-Phe 7 ]-MSH (Melanotan-I) determined that an optimal dose for ten daily subcutaneous injections is 0.16 mg/kg per day

The specific risks and dangers vary depending on the type of peptide, dosage, and individual factors

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However, some clinics offering the retatrutide-cagrilintide combination use a ratio of approximately 5:1 (retatrutide to cagrilintide), which at a retatrutide dose of 10-12 mg would put cagrilintide at 2.0-2.5 mg