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At the 12 mg maximum dose, participants achieved an unprecedented 28.3% average weight loss at 80 weeks

One theory of how anorexia is triggered is that calorie restriction and starvation mode flips a metaphorical switch in the brain of those who are predisposed, says Terry Schwartz, the interim executive director of the Eating Disorders Center for Treatment and Research at the University of California, San Diego

According to the company's About page, the Joi brand was created by co-founder Katy Whalen to "give women what I never had - a space to feel heard, supported, and empowered with the kind of care that's built for women, by women." Women considering GLP-1 medications may have questions related to hormonal interactions, perimenopause, menopause, or conditions like PCOS

Table 1 shows a selection of the most representative results obtained in this study