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Excess Fe 3+ is reduced to Fe 2+ by the metalloreductase STEAP3 and transported into the cytoplasm via ZRT/IRT-like protein 14 (ZIP14) and solute carrier family 11 member 2 (SLC11A2/DMT1), forming the LIP and leading to iron metabolic disorders ( 2 O 2 ) through the Fenton reaction to produce large amounts of hydroxyl radicals

It catalyzes the dismutation of two molecules of superoxide anion (O2) to hydrogen peroxide (H2O2) and molecular oxygen (O2), consequently rendering the potentially harmful superoxide anion less hazardous

30,32 A retrospective matched case-control study of 324 patients who underwent ACL reconstruction with meniscus repair (PRP vs control age: 91.6 11.2 vs 92.4 10.6) showed no significant difference in IKDC scores nor in the timing of return to activity nor postoperative complications among the intraoperative PRP injection group and the control group after 2 years 33 In addition, Bailey et al

Licensed Providers Lab-Guided Ongoing Support This treatment may be right for you if you identify with any of the following: Explore alternative treatments your provider may recommend Take the first step with a clinician-guided evaluation