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Description

A population association study of four candidate genes (hexokinase II, glucagon-like peptide-1 receptor, fatty acid binding protein-2, and apolipoprotein C-II) with type 2 diabetes and impaired glucose tolerance in Japanese subjects

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Furthermore, SCFAs upregulate the expression of Foxp3, a key transcription factor for regulatory T cells, through HDAC inhibition (208, 209), promoting Treg differentiation and suppressing the production of pro-inflammatory cytokines (210)

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Novo Nordisks oral formulation of semaglutide, approved for type 2 diabetes at doses up to 14 mg daily, has been studied for weight loss in non-diabetic populations

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