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Methods Here, we leveraged four datasets of PCOS and executed differential gene expression analysis, engaged in WGCNA, and harnessed machine learning algorithmsincluding RF, SVM-RFE, and LASSOto deeply explore the key genes that interact with senescence and sphingolipid metabolism in granulosa cells of PCOS

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The canonical activation pathway is triggered through the site-specific phosphorylation by an IB-kinase (IKK) complex in response to microbes, and proinflammatory cytokines