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[44] In the cytosol [edit] Methylcobalamin and 5-methyltetrahydrofolate are needed by methionine synthase in the methionine cycle to transfer a methyl group from 5-methyltetrahydrofolate to homocysteine, thereby generating tetrahydrofolate (THF) and methionine, which is used to make SAMe

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Uses: Dosage and Administration: The typical dosage is 0.09 mg/kg per day for five days, though this can change based on the patient's response and condition