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For instance, Eli Lilly is working on orforglipron, an oral GLP-1 drug that aims to provide a more flexible dosing regimen without the strict meal-timing requirements associated with oral semaglutide

doi:10.1002/ksa.12441 Guo H, Li Q, Zhang Z, et al

The comparison breaks down like this

Effect of continued weekly subcutaneous semaglutide vs placebo on weight loss maintenance in adults with overweight or obesity: the step 4 randomized clinical trial