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in the form of storage proteins such as Lsp (40)

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Although the C-terminal SAM-binding site is located away from the catalytic center, it was revealed that SAM binding induces a structural rearrangement of the catalytic core that relieves autoinhibition and stabilizes an activated conformation ( Historically, aminooxyacetic acid (AOAA) has been the most commonly used inhibitor of CBS (Whiteman et al., 2011