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We acknowledged in the CY 2026 PFS proposed rule that not all pharmacies that dispense 340B-eligible drugs are registered in the 340B OPAIS database, including covered entities with in-house pharmacies, and that units of 340B-eligible drugs dispensed from pharmacies not registered in the 340B OPAIS database would not be identified as 340B-eligible using the Prescriber-Pharmacy Methodology, and we solicited comment on ways to improve the methodology to enhance completeness and accuracy of the data sources used

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