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It functions by blocking an enzyme known as nicotinamide N-methyltransferase (NNMT), which is important for how the body stores fat and uses energy

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They can often get bad enough that they affect other areas of your life as well, and with some of the neurological symptoms, you may not be able to reverse them at all

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In patients treated with semaglutide, weight loss continued over 65 weeks and was sustained for up to 4 years

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