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If glutathione levels fall, tissue repair slows, leading to delayed healing and potential tissue damage

In AD, the amyloid hypothesis suggests primarily driven by the accumulation of A-peptide in the brain (Hardy and Selkoe, 2002)

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In addition, the AIM-HIGH trial demonstrated that the concurrent use of extended-release niacin (1500-2000 mg/day PO) and simvastatin does not result in a greater reduction in the incidence of cardiovascular events than simvastatin alone