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The FDA has approved its use for chronic weight management in adults with a body mass index (BMI) of 30 or more, or a BMI of 27 or more when accompanied by at least one weight-related condition such as high blood pressure, high cholesterol, or type 2 diabetes

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By inhibiting TGF- pathways and reducing collagen deposition, they protect podocytes and endothelial cells from injury, slowing CKD progression

Corneal confocal microscopy offers a noninvasive alternative for tracking small fiber changes over time