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Key takeaways GLP-1 medications do not inherently cause muscle wasting. Most weight lost on semaglutide or tirzepatide is fat , not muscle. Some lean-mass loss during weight loss reflects adaptive remodeling , not pathology. Adequate protein intake and resistance training significantly reduce muscle loss during GLP-1 therapy. Do GLP-1 Medications Cause Muscle Wasting

If you want a deeper look at related terminology, see Diabetic Nephropathy

Link to paper To view or add a comment, sign in Metabolomics and proteomics each provide powerful, complementary views of biology

GLP-1 promotes insulin secretion from pancreatic cells via activation of cAMP-mediated protein kinase A (PKA)