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The Saxagliptin Assessment of Vascular Outcomes (SAVOR-TIMI 53) study is a similar study in 12,000 patients comparing saxagliptin with placebo in diabetic patients with high cardiovascular risk

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Its most effective when combined with lifestyle changes and behavioral support, such as a calorie-restricted, nutrient-dense diet and regular physical activity at least three times a week. Abeyta also emphasizes that patients taking Wegovy should set realistic goals, follow dosing instructions, and administer weekly injections at the same time and day each week