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After switching from alogliptin 25 mg daily to dulaglutide 0.75 mg weekly, and reducing IDeg/Asp from 36 to 24 units/day while maintaining other antidiabetic drugs, glycemic control was effectively maintained during the subsequent hospitalization

She explained that many patients have spent years white-knuckling their way through cravings, and that struggle often eases once the drug shifts the underlying brain signals

The appetite-suppressing effects of GLP-1 receptor agonists represent one of their most clinically significant brain actions

Contraindications and cautions Researchers should exercise caution in several scenarios