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Research has shown that calorie-restricted diet interventions in random human subjects, while improving metabolic health, lead to a reduction in bacterial numbers and a reshuffling of the gut microbiota due to strict calorie restrictions (von Schwartzenberg et al., 2021)

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Microdosing and Weight Loss: What We Actually Know Search phrases like microdosing for weight loss , microdosing weight loss , and microdosing and weight loss reflect a common hope: that lower doses might still help with long-term weight management