Based on preclinical (animal and cellular) data only, inhibition of NNMT by 5-Amino-1MQ is theorised to: Raise intracellular NAD+ levels Activate SIRT1 and other sirtuins (proteins linked to metabolic regulation) Reduce fat cell (adipocyte) size and proliferation Improve insulin sensitivity These effects have been demonstrated in mouse models (Neelakantan et al., 2019), but robust human clinical trial data are currently absent
Comprehensive Health Benefits : Beyond fat loss, AOD 9604 may contribute to improved bone health and overall well-being
It is important to keep medication out of reach of children, and special care should be taken when administering B12 injections to children, including supervision and expert guidance
2) This study conducted by the research team of Heffernan et al investigated the biological effects of AOD9604, a synthetic peptide fragment of HGH, in various mouse models, including lean and obese mice, as well as wild-type (WT) and 3-adrenergic receptor knockout (3-KO) mice