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Its core pathological feature is excessive accumulation of adipose tissue, accompanied by abnormal proliferation, differentiation, and metabolic dysfunction of adipocytes, which in turn induce a series of complications including insulin resistance, nonalcoholic fatty liver disease, and cardiovascular diseases

Some research suggests MOTS-c may influence signaling associated with muscle metabolism

No regulatory authority Health Canada, the FDA, the EMA, the TGA, or any equivalent has cleared 5-Amino-1MQ for therapeutic use in humans or animals