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Description

[DOI] [PubMed] [Google Scholar] 490.Piehl E, Fernandez-Bustamante A

These research systems are designed to analyze total pathway coordination, ultra-high-density caloric-balance signaling , and signaling behavior under peak concentration conditions

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The final mathematical model, using Monte Carlo simulations (as implemented in the NONMEM software) and the final estimated parameters, allowed us to simulate, with a high level of accuracy, plasma drug levels as a function of dose, even for doses not directly tested