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10.1186/s12943-018-0856-3 115 LiuZ.ShiB.WangY.XuQ.GaoH.MaJ.et al (2022c)

The loss of glutathione in the HIV + macrophages has been shown to be related to decreased cell defense against Mycobacterium tuberculosis replication [52]

Defines, tones and smoothes orange peel skin

Critically, this mechanism is selective for senescent cells because non-senescent cells do not accumulate FOXO4 in PML bodies and do not depend on FOXO4-p53 sequestration for survival