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Limit Medications and Compounds That Increase Homocysteine A number of prescription drugs and natural compounds have been shown to increase homocysteine by interfering with folate absorption, or metabolism of homocysteine, including (35-38): Cholestyramine Colestipol Fenofibrate Levadopa Metformin Methotrexate Niacin Nitrous oxide Pemetrexed Phenytoin Pyrimethamine Sulfasalazine 17

Emotions such as anger, rage and resentment greatly increases iron retention in some individuals

The latter study also suggested that DSIP may also have beneficial effects on stage-4 sleep, which is also known as REM sleep when dreaming occurs

Isaka et al., 1996