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Drug class Mounjaro: Dual GIP + GLP-1 receptor agonist Wegovy: GLP-1 receptor agonist Active ingredient Mounjaro: Tirzepatide Wegovy: Semaglutide Dosing Both: Once-weekly subcutaneous injection Similar escalation schedules, but different titration protocols Mechanism Mounjaro: Targets two incretin pathways (GIP + GLP-1), enhancing metabolic and appetite effects Wegovy: Targets GLP-1 pathway only Weight loss efficacy Mounjaro: Up to ~15% weight reduction in clinical trials Wegovy: ~1015% average body weight reduction Clinical use Mounjaro: Often considered more potent option Wegovy: Established first-line GLP-1 obesity therapy Saxenda vs Wegovy Saxenda is a prescription injectable treatment used in adults who are obese or overweight

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