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1) Inflammation and Oxidative Stress Healthy people who took 20 mg of PQQ (for a 150-pound male) had a significant decrease in the levels of C-reactive protein (by 45% after 3 weeks) and IL-6

Signs of contamination or degradation: Cloudiness or turbidity (potential bacterial growth or precipitation) Visible particles or crystals (potential contamination or degradation products) Discolouration or browning (potential oxidative degradation) Visible mould growth (rare, but indicates severe contamination) Unpleasant or unusual odour (potential bacterial contamination) Action: If any of these signs are observed, discard the vial immediately

The elevated oxalate levels increase inflammation and fibrosis.[ref] Related article : Fatty liver disease NLRP3 inflammasome activation: The NLRP3 inflammasome is activated by increased ROS and calcium oxalate crystals

Until those data arrive, claims about meaningful, reproducible benefits should be treated as hypotheses